Etv5^tm1.2Xsun
Targeted Allele Detail

Summary

• Symbol: Etv5^tm1.2Xsun
• Name: ets variant 5; targeted mutation 1.2, Xin Sun
• MGI ID: MGI:3849049
• Gene: Etv5 Location: Chr16:22200063-22258320 bp, - strand Genetic Position: Chr16, 13.3 cM, cytoband B1
• Alliance: Etv5^tm1.2Xsun page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149477
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Germ line, cre mediated recombination removed exons 10 and 11. The deletion of the DNA binding domain is expected to produce a null allele. (J:149477)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Etv5 Mutation: 271 strains or lines available

References

• Original: J:149477 Zhang Z, et al., FGF-regulated Etv genes are essential for repressing Shh expression in mouse limb buds. Dev Cell. 2009 Apr;16(4):607-13
• All: 1 reference(s)