Hhex^tm1Jomb
Targeted Allele Detail

Summary

• Symbol: Hhex^tm1Jomb
• Name: hematopoietically expressed homeobox; targeted mutation 1, Joshua M Brickman
• MGI ID: MGI:3849291
• Synonyms: Hex^RS
• Gene: Hhex Location: Chr19:37423289-37429179 bp, + strand Genetic Position: Chr19, 32.28 cM, cytoband D1
• Alliance: Hhex^tm1Jomb page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149792
• Parent Cell Line: E14TG2a (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutation: Insertion
• Mutation details: A cassette containing a modified RFP (redstar), IRES, polyadenylation site, blasticidin resistance gene, and floxed hygro gene driven by a CMV promoter was fused inframe with the translation initiation codon. (J:149792)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hhex Mutation: 17 strains or lines available

References

• Original: J:149792 Morrison GM, et al., Anterior definitive endoderm from ESCs reveals a role for FGF signaling. Cell Stem Cell. 2008 Oct 9;3(4):402-15
• All: 1 reference(s)