Acp3^tm1Pivi
Targeted Allele Detail

Summary

• Symbol: Acp3^tm1Pivi
• Name: acid phosphatase 3; targeted mutation 1, Pirkko Vihko
• MGI ID: MGI:3849300
• Synonyms: PAP^delta3
• Gene: Acp3 Location: Chr9:104165439-104214921 bp, - strand Genetic Position: Chr9, 56.61 cM
• Alliance: Acp3^tm1Pivi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149872
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Exon 3 was deleted resulting in complete loss of the secretory and transmembrane PAP catalytic activity of the encoded protein. (J:149872)

Disease models

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Acp3 Mutation: 32 strains or lines available

References

• Original: J:149872 Zylka MJ, et al., Prostatic acid phosphatase is an ectonucleotidase and suppresses pain by generating adenosine. Neuron. 2008 Oct 9;60(1):111-22
• All: 8 reference(s)