Klf5^tm1Yfk
Targeted Allele Detail

Summary

• Symbol: Klf5^tm1Yfk
• Name: Kruppel-like transcription factor 5; targeted mutation 1, Yoshiaki Fujii-Kuriyama
• MGI ID: MGI:3849301
• Synonyms: Bteb2^-, Klf5^lacZ
• Gene: Klf5 Location: Chr14:99536127-99550848 bp, + strand Genetic Position: Chr14, 49.43 cM, cytoband E2.1
• Alliance: Klf5^tm1Yfk page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149868
• Parent Cell Line: E14 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 2 was replaced with a lacz-neomycin cassette. Correct targeting was confirmed by Southern blotting. (J:149868)

Expression

In Mice Carrying this Mutation:	24 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Klf5 Mutation: 37 strains or lines available

References

• Original: J:149868 Ema M, et al., Kruppel-like factor 5 is essential for blastocyst development and the normal self-renewal of mouse ESCs. Cell Stem Cell. 2008 Nov 6;3(5):555-67
• All: 3 reference(s)