Tg(Cd4-Klra1)6295Dl
Transgene Detail

Summary

• Symbol: Tg(Cd4-Klra1)6295Dl
• Name: transgene insertion 6295, David Lo
• MGI ID: MGI:3849441
• Synonyms: Ly-49A, Tg(Cd4-Klra1)1Dl
• Transgene: Tg(Cd4-Klra1)6295Dl Location: unknown
• Alliance: Tg(Cd4-Klra1)6295Dl page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Cd4-Klra1)6295Dl expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Klra1 (MGI:101907)

• Mutation details: The Ly-49A transgenic construct containing the mouse Klra1 (killer cell lectin-like receptor, subfamily A, member 1) gene under the control of a modified mouse CD4 antigen (Cd4) promoter (this promoter lacks the silencer element sequence suppressing expression in CD8 T cells) was injected into fertilized C57BL/6 mouse eggs. Founder line 6295 was established. (J:59307)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:59307 Pauza M, et al., Transgenic expression of Ly-49A in thymocytes alters repertoire selection. J Immunol. 2000 Jan 15;164(2):884-92
• All: 2 reference(s)