About   Help   FAQ
Tg(Kera-cre)KC4.3Wwk
Transgene Detail
Summary
Symbol: Tg(Kera-cre)KC4.3Wwk
Name: transgene insertion KC4.3, Winston W Y Kao
MGI ID: MGI:3849605
Synonyms: KC4.3, Kera-Cre
Transgene: Tg(Kera-cre)KC4.3Wwk  Location: unknown  
Alliance: Tg(Kera-cre)KC4.3Wwk page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Kera-cre)KC4.3Wwk expression driven by 1 gene
 
Mutation detailsA minigene containing a 3.2 kb fragment 5' of the transcription start site of the Kera gene, exon 1 (172 bp), intron 1 (1.4 kb), exon 2 (7 bp) preceding the ATG start codon of the Kera mRNA, and a cre minigene with IRES and nuclear localization sequences (NLS) followed by the SV40 polyadenylation (pA) signal, was injected into FVB/N oocytes. Mice were crossed with R26R reporter mice to assess cre activity. Founder line KC4.3, showing strong expression and line KC4.1 with moderate expression were characterized further. (J:149921)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Kera (species not specified)
Summary of all recombinase alleles driven by Kera.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Disease models
Loading...
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:149921 Weng DY, et al., Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice. Mol Vis. 2008;14:562-71
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/29/2024
MGI 6.24
The Jackson Laboratory