Tg(Kera-cre)KC4.3Wwk
Transgene Detail
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Symbol: |
Tg(Kera-cre)KC4.3Wwk |
Name: |
transgene insertion KC4.3, Winston W Y Kao |
MGI ID: |
MGI:3849605 |
Synonyms: |
KC4.3, Kera-Cre |
Transgene: |
Tg(Kera-cre)KC4.3Wwk Location: unknown
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Alliance: |
Tg(Kera-cre)KC4.3Wwk page
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Transgene Type: |
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Transgenic (Recombinase) |
Mutation: |
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Insertion
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Tg(Kera-cre)KC4.3Wwk expression driven by
1 gene
Transgene expression driven by:
Organism |
Driver Gene |
Note |
Not Specified |
Kera |
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Mutation details: A minigene containing a 3.2 kb fragment 5' of the transcription start site of the Kera gene, exon 1 (172 bp), intron 1 (1.4 kb), exon 2 (7 bp) preceding the ATG start codon of the Kera mRNA, and a cre minigene with IRES and nuclear localization sequences (NLS) followed by the SV40 polyadenylation (pA) signal, was injected into FVB/N oocytes. Mice were crossed with R26R reporter mice to assess cre activity. Founder line KC4.3, showing strong expression and line KC4.1 with moderate expression were characterized further.
(J:149921)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Kera
(species not specified)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:149921 Weng DY, et al., Promiscuous recombination of LoxP alleles during gametogenesis in cornea Cre driver mice. Mol Vis. 2008;14:562-71 |
All: |
5 reference(s) |
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