Gcnt3^tm1.1Jxm
Targeted Allele Detail

Summary

• Symbol: Gcnt3^tm1.1Jxm
• Name: glucosaminyl (N-acetyl) transferase 3, mucin type; targeted mutation 1.1, Jamey Marth
• MGI ID: MGI:3849681
• Synonyms: C2GnT1^-
• Gene: Gcnt3 Location: Chr9:69938778-69945370 bp, - strand Genetic Position: Chr9, 39.2 cM, cytoband D
• Alliance: Gcnt3^tm1.1Jxm page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149909
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Mice containing the floxed Gcnt3^tm1Jxm allele were crossed with cre transgenic mice to create a null allele by excision of the single coding exon. Excision of the exon was confirmed by Southern blotting of homozygote tissue extracts. (J:149909)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gcnt3 Mutation: 25 strains or lines available

References

• Original: J:149909 Stone EL, et al., Glycosyltransferase function in core 2-type protein O glycosylation. Mol Cell Biol. 2009 Jul;29(13):3770-82
• All: 4 reference(s)