Tg(Ckm-CUGBP1)1036Coop
Transgene Detail
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Symbol: |
Tg(Ckm-CUGBP1)1036Coop |
Name: |
transgene insertion 1036, Thomas A Cooper |
MGI ID: |
MGI:3850090 |
Synonyms: |
MCKCUG-BP1 |
Transgene: |
Tg(Ckm-CUGBP1)1036Coop Location: unknown
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Alliance: |
Tg(Ckm-CUGBP1)1036Coop page
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Transgene Type: |
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Transgenic (Inserted expressed sequence) |
Mutation: |
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Insertion
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Tg(Ckm-CUGBP1)1036Coop expresses
1 gene
Transgene expresses:
Organism |
Expressed Gene |
Homolog in Mouse |
Note |
human |
CELF1 (10658) |
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Mutation details: A human CUGBP1, 'A' form, clone, containing an N-terminal FLAG epitope tag, was expressed in mice under the control of a mouse creatine kinase (MCK) promoter, enhancer, the untranslated exon 1, and intron 1 and bovine growth hormone 3' flanking genomic segment for proper mRNA 3' end formation. In addition to line 1036, linse 1032 and 1039 were also established. Western blot analysis showed that transgene expression is approximately 1 times the endogenous level.
(J:99370)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Original: |
J:99370 Ho TH, et al., Transgenic mice expressing CUG-BP1 reproduce splicing mis-regulation observed in myotonic dystrophy. Hum Mol Genet. 2005 Jun 1;14(11):1539-47 |
All: |
3 reference(s) |
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