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Tg(Ckm-CUGBP1)1036Coop
Transgene Detail
Summary
Symbol: Tg(Ckm-CUGBP1)1036Coop
Name: transgene insertion 1036, Thomas A Cooper
MGI ID: MGI:3850090
Synonyms: MCKCUG-BP1
Transgene: Tg(Ckm-CUGBP1)1036Coop  Location: unknown  
Alliance: Tg(Ckm-CUGBP1)1036Coop page
Transgene
origin
Strain of Origin:  FVB
Transgene
description
Transgene Type:    Transgenic (Inserted expressed sequence)
Mutation:    Insertion
 
Tg(Ckm-CUGBP1)1036Coop expresses 1 gene
 
Mutation detailsA human CUGBP1, 'A' form, clone, containing an N-terminal FLAG epitope tag, was expressed in mice under the control of a mouse creatine kinase (MCK) promoter, enhancer, the untranslated exon 1, and intron 1 and bovine growth hormone 3' flanking genomic segment for proper mRNA 3' end formation. In addition to line 1036, linse 1032 and 1039 were also established. Western blot analysis showed that transgene expression is approximately 1 times the endogenous level. (J:99370)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:99370 Ho TH, et al., Transgenic mice expressing CUG-BP1 reproduce splicing mis-regulation observed in myotonic dystrophy. Hum Mol Genet. 2005 Jun 1;14(11):1539-47
All:  3 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory