Gt(ROSA)26Sor^{tm1(CAG-EGFP)Blh}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(CAG-EGFP)Blh}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Brigid L Hogan
• MGI ID: MGI:3850169
• Synonyms: GFPf, Rosa26R-CAG-fGFP
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(CAG-EGFP)Blh} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:149822
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, Reporter)
• Mutation: Insertion
• Mutation details: A construct containing the chicken beta-actin promoter (CAG) with a loxP-STOP-loxP cassette preceding a farnesylated enhanced GFP sequence (eGFP-f) was inserted into intron 1 of the Gt(ROSA)26Sor locus via homologous recombination. Cre-mediated recombination of this allele results in the expression of the EGFP reporter driven by the CAG promoter. (J:149822)

Tumor Data

List all tumor models in MMHCdb carrying Gt(ROSA)26Sor^{tm1(CAG-EGFP)Blh}

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:149822 Rawlins EL, et al., The role of Scgb1a1+ Clara cells in the long-term maintenance and repair of lung airway, but not alveolar, epithelium. Cell Stem Cell. 2009 Jun 5;4(6):525-34
• All: 22 reference(s)