Gucy2gtm1Rbya
Targeted Allele Detail
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| Symbol: |
Gucy2gtm1Rbya |
| Name: |
guanylate cyclase 2g; targeted mutation 1, Ruey-Bing Yang |
| MGI ID: |
MGI:3850214 |
| Synonyms: |
GC-G- |
| Gene: |
Gucy2g Location: Chr19:55186531-55229668 bp, - strand Genetic Position: Chr19, 51.18 cM, cytoband D2
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| Alliance: |
Gucy2gtm1Rbya page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:150175
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: Exon 6 was replaced with a neo cassette via homologous recombination. RT-PCR and western blot analysis confirmed the absence of expression in the kidney and kidney and sperm, respectively, from homozygous mice.
(J:150175)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Gucy2g Mutation: |
60 strains or lines available
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| Original: |
J:150175 Lin H, et al., Disruption of guanylyl cyclase-G protects against acute renal injury. J Am Soc Nephrol. 2008 Feb;19(2):339-48 |
| All: |
6 reference(s) |
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Analysis Tools
