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Suz12tm1Xmir
Targeted Allele Detail
Summary
Symbol: Suz12tm1Xmir
Name: SUZ12 polycomb repressive complex 2 subunit; targeted mutation 1, Xavier Miro
MGI ID: MGI:3850246
Gene: Suz12  Location: Chr11:79883932-79924949 bp, + strand  Genetic Position: Chr11, 47.36 cM
Alliance: Suz12tm1Xmir page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:150128
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutations:    Insertion, Intragenic deletion
    Exons 12 through 16 were replaced with a lacZ gene and neo cassette. (J:150128)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 25 assay results
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Suz12 Mutation:  61 strains or lines available
References
Original:  J:150128 Miro X, et al., Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube. Dis Model Mech. 2009 Jul-Aug;2(7-8):412-8
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory