Suz12^tm1Xmir
Targeted Allele Detail

Summary

• Symbol: Suz12^tm1Xmir
• Name: SUZ12 polycomb repressive complex 2 subunit; targeted mutation 1, Xavier Miro
• MGI ID: MGI:3850246
• Gene: Suz12 Location: Chr11:79883932-79924949 bp, + strand Genetic Position: Chr11, 47.36 cM
• Alliance: Suz12^tm1Xmir page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150128
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exons 12 through 16 were replaced with a lacZ gene and neo cassette. (J:150128)

Expression

In Mice Carrying this Mutation:	25 assay results
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Suz12 Mutation: 61 strains or lines available

References

• Original: J:150128 Miro X, et al., Haploinsufficiency of the murine polycomb gene Suz12 results in diverse malformations of the brain and neural tube. Dis Model Mech. 2009 Jul-Aug;2(7-8):412-8
• All: 1 reference(s)