Tg(Cd79b-TCL1A)BKTeit
Transgene Detail

Summary

• Symbol: Tg(Cd79b-TCL1A)BKTeit
• Name: transgene insertion BK, Michael Teitell
• MGI ID: MGI:3850366
• Synonyms: TCL1-tg
• Transgene: Tg(Cd79b-TCL1A)BKTeit Location: unknown
• Alliance: Tg(Cd79b-TCL1A)BKTeit page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F1

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Cd79b-TCL1A)BKTeit expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TCL1A (8115)

  Tcl1	(MGI:1097166)

• Mutation details: A transgenic construct containing 381 bp of coding sequence of the human T-cell leukemia/lymphoma 1 gene (TCL1A) under the control of the mouse CD79B antigen ( Cd79b) minimal promoter was injected into fertilized (C57BL/6 x C3H)F1 mouse eggs. Founder line BK was established. (J:79703)

Expression

In Structures Affected by this Mutation:

7 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:79703 Hoyer KK, et al., Dysregulated TCL1 promotes multiple classes of mature B cell lymphoma. Proc Natl Acad Sci U S A. 2002 Oct 29;99(22):14392-7
• All: 3 reference(s)