Tg(Prl-tTA)6-5Jek
Transgene Detail
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| Symbol: |
Tg(Prl-tTA)6-5Jek |
| Name: |
transgene insertion 6-5, Jeffrey E Kudlow |
| MGI ID: |
MGI:3850376 |
| Synonyms: |
Prl-tTA |
| Transgene: |
Tg(Prl-tTA)6-5Jek Location: unknown
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| Alliance: |
Tg(Prl-tTA)6-5Jek page
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| Strain of Origin: |
(C57BL/6 x SJL)
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| Transgene Type: |
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Transgenic (Transactivator) |
| Mutation: |
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Insertion
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Mutation details: The PRL-tTA transgene was designed with a 3.2 kb promoter sequence from the rat prolactin (Prl) gene, a tetracycline-regulated transactivator (tTA) gene, and an SV40 intron/polyA sequence. This 5.2 kb transgene was microinjected into one-cell (C57BL/6 x SJL) mouse zygotes. Mice from founder line 6-5 were bred with C57BL/6;SJL wildtype mice to establish the colony.
(J:68692)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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| Original: |
J:68692 Roh M, et al., Stage-sensitive blockade of pituitary somatomammotrope development by targeted expression of a dominant negative epidermal growth factor receptor in transgenic mice. Mol Endocrinol. 2001 Apr;15(4):600-13 |
| All: |
1 reference(s) |
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Analysis Tools
