Tg(Gh1-rtTA)4-3Jek
Transgene Detail
|
|
| Symbol: |
Tg(Gh1-rtTA)4-3Jek |
| Name: |
transgene insertion 4-3, Jeffrey E Kudlow |
| MGI ID: |
MGI:3850379 |
| Synonyms: |
GH-rtTA |
| Transgene: |
Tg(Gh1-rtTA)4-3Jek Location: unknown
|
| Alliance: |
Tg(Gh1-rtTA)4-3Jek page
|
|
| Strain of Origin: |
(C57BL/6 x SJL)
|
|
| Transgene Type: |
|
Transgenic (Transactivator) |
| Mutation: |
|
Insertion
|
| |
|
Mutation details: The GH-rtTA transgene was designed with a 1.7 kb promoter sequence from the rat growth hormone (Gh1) gene, a reverse tetracycline-regulated transactivator (rtTA) gene, and an SV40 intron/polyA sequence. This 4.5 kb transgene was microinjected into one-cell (C57BL/6 x SJL) mouse zygotes. Mice from founder line 4-3 were bred with C57BL/6;SJL wildtype mice to establish the colony.
(J:68692)
|
|
|
View phenotypes and curated references for all genotypes (concatenated display).
|
| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
|
|
| Original: |
J:68692 Roh M, et al., Stage-sensitive blockade of pituitary somatomammotrope development by targeted expression of a dominant negative epidermal growth factor receptor in transgenic mice. Mol Endocrinol. 2001 Apr;15(4):600-13 |
| All: |
1 reference(s) |
|
Analysis Tools
