Tg(GFAP-CRYAB)141.6Mes
Transgene Detail

Summary

• Symbol: Tg(GFAP-CRYAB)141.6Mes
• Name: transgene insertion 141.6, Albee Messing
• MGI ID: MGI:3850461
• Synonyms: Cryab^Tg, CryabTg
• Transgene: Tg(GFAP-CRYAB)141.6Mes Location: unknown
• Alliance: Tg(GFAP-CRYAB)141.6Mes page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(GFAP-CRYAB)141.6Mes expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  hamster	Cryab (101827485)

• Mutation details: A transgenic construct containing the hamster Cryab, alpha B crystalline gene under the control of the human GFAP, glial fibrillary acidic protein, promoter was injected into fertilized FVB/N mouse eggs. Founder line 141.6 was subsequently established. (J:146191)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:146191 Hagemann TL, et al., Suppression of GFAP toxicity by alphaB-crystallin in mouse models of Alexander disease. Hum Mol Genet. 2009 Apr 1;18(7):1190-9
• All: 2 reference(s)