Rheb^tm1Pfw
Targeted Allele Detail

Summary

• Symbol: Rheb^tm1Pfw
• Name: Ras homolog enriched in brain; targeted mutation 1, Paul Worley
• MGI ID: MGI:3850507
• Synonyms: Rheb1f, Rheb^fl
• Gene: Rheb Location: Chr5:25007821-25047359 bp, - strand Genetic Position: Chr5, 11.93 cM
• Alliance: Rheb^tm1Pfw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150108
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted upstream of exon 3 and an FRT flanked PGK-neo cassette and second loxP site were inserted downstream of exon 3 via homologous recombination. (J:150108, J:168571)

Expression

In Mice Carrying this Mutation:	2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	6 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rheb Mutation: 26 strains or lines available

References

• Original: J:150108 Delgoffe GM, et al., The mTOR kinase differentially regulates effector and regulatory T cell lineage commitment. Immunity. 2009 Jun 19;30(6):832-44
• All: 28 reference(s)