Map4k1^tm1Ssaw
Targeted Allele Detail

Summary

• Symbol: Map4k1^tm1Ssaw
• Name: mitogen-activated protein kinase kinase kinase kinase 1; targeted mutation 1, Sansana Sawasdikosol
• MGI ID: MGI:3850713
• Synonyms: HPK1, HPK1^-
• Gene: Map4k1 Location: Chr7:28681506-28702704 bp, + strand Genetic Position: Chr7, 16.94 cM, cytoband A3
• Alliance: Map4k1^tm1Ssaw page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150295
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Not Specified
• A neomycin cassette was inserted in exon 1. (J:165021)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Map4k1 Mutation: 55 strains or lines available

References

• Original: J:150295 Alzabin S, et al., Hematopoietic progenitor kinase 1 is a negative regulator of dendritic cell activation. J Immunol. 2009 May 15;182(10):6187-94
• All: 4 reference(s)