Gpsm2^tm1.2Fuma
Targeted Allele Detail

Summary

• Symbol: Gpsm2^tm1.2Fuma
• Name: G-protein signalling modulator 2 (AGS3-like, C. elegans); targeted mutation 1.2, Fumio Matsuzaki
• MGI ID: MGI:3850860
• Synonyms: LGN^deltaC
• Gene: Gpsm2 Location: Chr3:108585954-108629625 bp, - strand Genetic Position: Chr3, 47.53 cM, cytoband F3
• Alliance: Gpsm2^tm1.2Fuma page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:132370
• Parent Cell Line: TT2 (ES Cell)
• Strain of Origin: (C57BL/6NCrlj x CBA/JNCrlj)F1

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: Gpsm2 mice were crossed with an unspecified cre-deleter mouse line. Cre expression resulted in the excision of exons 13, 14, and the coding protion of exon 15. (J:132370)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gpsm2 Mutation: 26 strains or lines available

References

• Original: J:132370 Konno D, et al., Neuroepithelial progenitors undergo LGN-dependent planar divisions to maintain self-renewability during mammalian neurogenesis. Nat Cell Biol. 2008 Jan;10(1):93-101
• All: 4 reference(s)