Aifm1^tm2.1Pngr
Targeted Allele Detail

Summary

• Symbol: Aifm1^tm2.1Pngr
• Name: apoptosis-inducing factor, mitochondrion-associated 1; targeted mutation 2.1, Josef M Penninger
• MGI ID: MGI:3851178
• Synonyms: Aif^deltaex7
• Gene: Aifm1 Location: ChrX:47563821-47602440 bp, - strand Genetic Position: ChrX, 25.68 cM, cytoband A6
• Alliance: Aifm1^tm2.1Pngr page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:111066
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Germ line, cre mediated recombination removes exon 7. (J:111066)

Expression

In Mice Carrying this Mutation:	7 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Aifm1 Mutation: 11 strains or lines available

References

• Original: J:111066 Brown D, et al., Loss of Aif function causes cell death in the mouse embryo, but the temporal progression of patterning is normal. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9918-23
• All: 1 reference(s)