Tg(Cd8a-cre)1Itan
Transgene Detail

Summary

• Symbol: Tg(Cd8a-cre)1Itan
• Name: transgene insertion 1, Ichiro Taniuchi
• MGI ID: MGI:3851193
• Synonyms: E8I-Cre, E8I^Cre.GFP
• Transgene: Tg(Cd8a-cre)1Itan Location: unknown
• Alliance: Tg(Cd8a-cre)1Itan page

Transgene origin

• Strain of Origin: C57BL/6

Transgene description

• Transgene Type: Transgenic (Recombinase, Reporter)
• Mutation: Insertion
• Tg(Cd8a-cre)1Itan expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  Not Specified	Cd8a

• Mutation details: The 1.6 kb core of the E8I Cd8 locus enhancer region was inserted in front of the Cd8a promoter, and cre recombinase cDNA and an IRES-GFP-polyA cassette were inserted after the promoter to generated the transgene construct. (J:141009)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Cd8a (species not specified) Summary of all recombinase alleles driven by Cd8a.

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:141009 Maekawa Y, et al., Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity. Nat Immunol. 2008 Oct;9(10):1140-7
• All: 49 reference(s)