Slc46a1^tm1Hija
Targeted Allele Detail

Summary

• Symbol: Slc46a1^tm1Hija
• Name: solute carrier family 46, member 1; targeted mutation 1, Hieronim Jakubowski
• MGI ID: MGI:3851364
• Synonyms: Pcft^-
• Gene: Slc46a1 Location: Chr11:78356527-78362771 bp, + strand Genetic Position: Chr11, 46.74 cM
• Alliance: Slc46a1^tm1Hija page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150548
• Parent Cell Line: Lex-1 (ES Cell)
• Strain of Origin: 129S5/SvEvBrd

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Exons 1 through 3 were replaced with a lacZ/neo cassette. (J:150548, J:173282)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc46a1 Mutation: 23 strains or lines available

References

• Original: J:150548 Jakubowski H, et al., Genetic or nutritional disorders in homocysteine or folate metabolism increase protein N-homocysteinylation in mice. FASEB J. 2009 Jun;23(6):1721-7
• All: 3 reference(s)