Tg(Mt1-CBS)25Waku
Transgene Detail

Summary

• Symbol: Tg(Mt1-CBS)25Waku
• Name: transgene insertion 25, Warren Kruger
• MGI ID: MGI:3851387
• Synonyms: Tg-hCSB
• Transgene: Tg(Mt1-CBS)25Waku Location: unknown
• Alliance: Tg(Mt1-CBS)25Waku page

Transgene origin

• Strain of Origin: (C57BL/6 x C3H)F2

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Mt1-CBS)25Waku expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  CBS (875)

  Cbs	(MGI:88285)

• Mutation details: The mouse promoter was used to drive zinc-inducible expression of the wild-type human cDNA. Three lines were created (2, 21, and 25) and line 25 was selected as the representative line. (J:98869)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:98869 Wang L, et al., Modulation of cystathionine beta-synthase level regulates total serum homocysteine in mice. Circ Res. 2004 May 28;94(10):1318-24
• All: 10 reference(s)