Tg(tetO-Dusp6)1Jmol
Transgene Detail

Summary

• Symbol: Tg(tetO-Dusp6)1Jmol
• Name: transgene insertion 1, Jeffery D Molkentin
• MGI ID: MGI:3851561
• Synonyms: Tg(DUSP6)
• Transgene: Tg(tetO-Dusp6)1Jmol Location: unknown
• Alliance: Tg(tetO-Dusp6)1Jmol page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Epitope tag, Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO-Dusp6)1Jmol expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Dusp6 (MGI:1914853)

• Mutation details: A tetracycline-responsive element (TRE; tetO) and mouse alpha myosin heavy chain minimal promoter regulate expression of Myc-tagged mouse Dusp6. The transgenic line was created and maintained on an FVB background. Copy number was not determined. (J:124903)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:124903 Purcell NH, et al., Genetic inhibition of cardiac ERK1/2 promotes stress-induced apoptosis and heart failure but has no effect on hypertrophy in vivo. Proc Natl Acad Sci U S A. 2007 Aug 28;104(35):14074-9
• All: 1 reference(s)