Tg(Myh6-MEF2A)1Jmol
Transgene Detail

Summary

• Symbol: Tg(Myh6-MEF2A)1Jmol
• Name: transgene insertion 1, Jeffery D Molkentin
• MGI ID: MGI:3851584
• Synonyms: MEF2A TG
• Transgene: Tg(Myh6-MEF2A)1Jmol Location: unknown
• Alliance: Tg(Myh6-MEF2A)1Jmol page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(Myh6-MEF2A)1Jmol expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  MEF2A (4205)

  Mef2a

  (MGI:99532)

• Mutation details: The mouse cardiac alpha myosin heavy chain (Myh6) promoter drives expression of full-length human MEF2A cDNA. (J:111573)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:111573 Xu J, et al., Myocyte enhancer factors 2A and 2C induce dilated cardiomyopathy in transgenic mice. J Biol Chem. 2006 Apr 7;281(14):9152-62
• All: 2 reference(s)