Zbtb18^tm1Haok
Targeted Allele Detail

Summary

• Symbol: Zbtb18^tm1Haok
• Name: zinc finger and BTB domain containing 18; targeted mutation 1, Haruo Okado
• MGI ID: MGI:3851929
• Synonyms: RP58^-
• Gene: Zbtb18 Location: Chr1:177269917-177278330 bp, + strand Genetic Position: Chr1, 82.72 cM, cytoband H3
• Alliance: Zbtb18^tm1Haok page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150768
• Parent Cell Line: GS1 (ES Cell)
• Strain of Origin: 129/Sv

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exon 1 was replaced with a neo cassette. The absence of protein expression was confirmed by western blot analysis on embryonic brain extracts. (J:150768)

Expression

In Mice Carrying this Mutation:	18 assay results 2 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	8 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Zbtb18 Mutation: 26 strains or lines available

References

• Original: J:150768 Okado H, et al., The transcriptional repressor RP58 is crucial for cell-division patterning and neuronal survival in the developing cortex. Dev Biol. 2009 Jul 15;331(2):140-51
• All: 5 reference(s)