Et(cre/ERT2)6959Rdav
Transgene Detail

Summary

• Symbol: Et(cre/ERT2)6959Rdav
• Name: enhancer trap 6959, Ron Davis
• MGI ID: MGI:3852339
• Transgene: Et(cre/ERT2)6959Rdav Location: unknown
• Alliance: Et(cre/ERT2)6959Rdav page

Transgene origin

• Strain of Origin: C57BL/6J
• Project Collection: Neuroscience Blueprint cre

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Et(cre/ERT2)6959Rdav expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Et(cre/ERT2)6959Rdav (MGI:3852237)

• Mutation details: An enhancer trap transgenic approach was used to generate these mice. The hsyn-bgi-cre:ERT2-bGHpA transgene was designed with the human synapsin minimal promoter (hsyn) minimal promoter driving a cre-ER^T2 fusion gene (cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 6959 was established on a C57BL/6J genetic background. (J:150856)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Et(cre/ERT2)6959Rdav (mouse) Summary of all recombinase alleles driven by Et(cre/ERT2)6959Rdav. Comparative matrix view of recombinase activities Alliance mouse Et(cre/ERT2)6959Rdav gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009
• All: 2 reference(s)