Et(cre/ERT2)7089Rdav
Transgene Detail

Summary

• Symbol: Et(cre/ERT2)7089Rdav
• Name: enhancer trap 7089, Ron Davis
• MGI ID: MGI:3852340
• Transgene: Et(cre/ERT2)7089Rdav Location: unknown
• Alliance: Et(cre/ERT2)7089Rdav page

Transgene origin

• Strain of Origin: C57BL/6J
• Project Collection: Neuroscience Blueprint cre

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Et(cre/ERT2)7089Rdav expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Et(cre/ERT2)7089Rdav (MGI:3852238)

• Mutation details: An enhancer trap transgenic approach was used to generate these mice. The hsyn-bgi-cre:ERT2-bGHpA transgene was designed with the human synapsin minimal promoter (hsyn) minimal promoter driving a cre-ER^T2 fusion gene (cre recombinase fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain).A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 7089 was established on a C57BL/6J genetic background. (J:150856)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Et(cre/ERT2)7089Rdav (mouse) Summary of all recombinase alleles driven by Et(cre/ERT2)7089Rdav. Comparative matrix view of recombinase activities Alliance mouse Et(cre/ERT2)7089Rdav gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009
• All: 2 reference(s)