Et(icre/ERT2)10596Rdav
Transgene Detail

Summary

• Symbol: Et(icre/ERT2)10596Rdav
• Name: enhancer trap 10596, Ron Davis
• MGI ID: MGI:3852351
• Transgene: Et(icre/ERT2)10596Rdav Location: unknown
• Alliance: Et(icre/ERT2)10596Rdav page

Transgene origin

• Strain of Origin: C57BL/6J
• Project Collection: Neuroscience Blueprint cre

Transgene description

• Transgene Type: Transgenic (Inducible, Recombinase)
• Inducer: tamoxifen
• Mutation: Insertion
• Et(icre/ERT2)10596Rdav expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Et(icre/ERT2)10596Rdav (MGI:3852320)

• Mutation details: An enhancer trap transgenic approach was used to generate these mice. The hsyn-bgi-cre:ERT2-bGHpA transgene was designed with the human synapsin minimal promoter (hsyn) minimal promoter driving an icre-ER^T2 fusion gene (a codon-improved cre recombinase sequence fused to a G400V/M543A/L544A triple mutation of the human estrogen receptor ligand binding domain). A beta globin intron separates the promoter from the cre gene and the bovine growth hormone polyadenylation signal follows the cre sequence. This transgene was injected into C57BL/6J embryos. Founder line 10596 was established on a C57BL/6J genetic background. (J:150856)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Et(icre/ERT2)10596Rdav (mouse) Summary of all recombinase alleles driven by Et(icre/ERT2)10596Rdav. Comparative matrix view of recombinase activities Alliance mouse Et(icre/ERT2)10596Rdav gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:150856 Davis R, Large-scale enhancer trap project to generate transgenic cre alleles by Ron Davis at Baylor University. MGI Direct Data Submission. 2009
• All: 3 reference(s)