Hinfp^tm1Gss
Targeted Allele Detail

Summary

• Symbol: Hinfp^tm1Gss
• Name: histone H4 transcription factor; targeted mutation 1, Gary S Stein
• MGI ID: MGI:3852353
• Synonyms: Hinfp^LacZ
• Gene: Hinfp Location: Chr9:44203737-44216968 bp, - strand Genetic Position: Chr9, 24.84 cM
• Alliance: Hinfp^tm1Gss page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:150791
• Parent Cell Line: AB1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1⁺

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Exons 2 through 9 were replaced with a lacZ and neo cassette. The presence of a fusion protein was confirmed by western blot analysis on ES cells. (J:150791)

Expression

In Mice Carrying this Mutation:	52 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hinfp Mutation: 26 strains or lines available

References

• Original: J:150791 Xie R, et al., The histone gene activator HINFP is a nonredundant cyclin E/CDK2 effector during early embryonic cell cycles. Proc Natl Acad Sci U S A. 2009 Jul 28;106(30):12359-64
• All: 4 reference(s)