Gnrhr^{Gt(181A6)Cmhd}
Gene trapped Allele Detail

Summary

• Symbol: Gnrhr^{Gt(181A6)Cmhd}
• Name: gonadotropin releasing hormone receptor; gene trap 181A6, Centre for Modeling Human Disease
• MGI ID: MGI:3855285
• Synonyms: Gnrhr^gt1NMS, Gnrhr^{Gt(CMHD-GT_181A6-3)Cmhd}, GT-Gnrhr
• Gene: Gnrhr Location: Chr5:86328613-86345760 bp, - strand Genetic Position: Chr5, 43.56 cM
• Alliance: Gnrhr^{Gt(181A6)Cmhd} page

Mutation origin

• Mutant Cell Line: 181A6
• Germline Transmission: Earliest citation of germline transmission: J:158384
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: Gen-SD5
• Mutation details: The construct contains a splice acceptor site upstream of the beta-galactosidase (beta-gal) gene followed by three stop codons and a phosphoglycerate kinase promoter driven neomycin gene followed by another three stop codons and a splice donor site. The insertion of the vector into intron 1 produces an exon 1-beta-gal fusion protein. (J:158384)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CMHD-GT_181A6-3	CW847943 ; (MGI Seq Detail)	3' RACE	Chr5:86329872-86333345 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  1 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

16 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gnrhr Mutation: 20 strains or lines available

Notes

This gene trap is no longer available through the Toronto Centre for Phenogenomics.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)