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Stk24Gt(AM0826)Wtsi
Gene trapped Allele Detail
Summary
Symbol: Stk24Gt(AM0826)Wtsi
Name: serine/threonine kinase 24; gene trap AM0826, Wellcome Trust Sanger Institute
MGI ID: MGI:3856801
Synonyms: Stk24h
Gene: Stk24  Location: Chr14:121523755-121617423 bp, - strand  Genetic Position: Chr14, 64.95 cM
Alliance: Stk24Gt(AM0826)Wtsi page
Mutation
origin
Mutant Cell Line:  AM0826
Germline Transmission:  Earliest citation of germline transmission: J:256076
Parent Cell Line:  E14TG2a.4 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Project Collection: Sanger Inst. Gene Trap Res.
Mutation
description
Allele Type:    Gene trapped (Hypomorph)
Mutation:    Insertion of gene trap vector     Vector: pGT0lxr
 
Mutation detailsA gene trap vector, containing a beta-galactosidase and neomycin resistance fusion gene cassette, inserted into intron 1. Encoded protein content in neutrophils of homozygous mice was reduced by 90%. (J:256076)
Sequence Tags: 
Sequence tag details (1 tag)
Genome Context: 
Genome Browser view of this mutation
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Stk24 Mutation:  33 strains or lines available
References
Original:  J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008;
All:  5 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
10/29/2024
MGI 6.24
The Jackson Laboratory