Stk24^{Gt(AM0826)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Stk24^{Gt(AM0826)Wtsi}
• Name: serine/threonine kinase 24; gene trap AM0826, Wellcome Trust Sanger Institute
• MGI ID: MGI:3856801
• Synonyms: Stk24^h
• Gene: Stk24 Location: Chr14:121523755-121617423 bp, - strand Genetic Position: Chr14, 64.95 cM
• Alliance: Stk24^{Gt(AM0826)Wtsi} page

Mutation origin

• Mutant Cell Line: AM0826
• Germline Transmission: Earliest citation of germline transmission: J:256076
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: A gene trap vector, containing a beta-galactosidase and neomycin resistance fusion gene cassette, inserted into intron 1. Encoded protein content in neutrophils of homozygous mice was reduced by 90%. (J:256076)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AM0826	CW989516 ; (MGI Seq Detail)	5' RACE	Chr14:121574833-121617416 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  27 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Stk24 Mutation: 33 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 5 reference(s)