Sfpq^{Gt(BC0256)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Sfpq^{Gt(BC0256)Wtsi}
• Name: splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated); gene trap BC0256, Wellcome Trust Sanger Institute
• MGI ID: MGI:3858266
• Gene: Sfpq Location: Chr4:126915117-126930806 bp, + strand Genetic Position: Chr4, 61.2 cM
• Alliance: Sfpq^{Gt(BC0256)Wtsi} page

Mutation origin

• Mutant Cell Line: BC0256
• Germline Transmission: Earliest citation of germline transmission: J:189236
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT2lxr
• Mutation details: In heterozygous mice up to a 2-fold reduction in both RNA and protein levels is detected in multiple tissues. (J:189236)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  BC0256	CW991058 ; (MGI Seq Detail)	5' RACE	Chr4:126915089-126915350 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  15 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sfpq Mutation: 29 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)