Sel1l^{Gt(CA0017)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Sel1l^{Gt(CA0017)Wtsi}
• Name: sel-1 suppressor of lin-12-like (C. elegans); gene trap CA0017, Wellcome Trust Sanger Institute
• MGI ID: MGI:3864670
• Synonyms: Sel1l^betageo
• Gene: Sel1l Location: Chr12:91772817-91815931 bp, - strand Genetic Position: Chr12, 45.02 cM, cytoband E
• Alliance: Sel1l^{Gt(CA0017)Wtsi} page

Impaired pancreatic epithelial growth and branching morphogenesis in Sel1l^{Gt(CA0017)Wtsi}/Sel1l^{Gt(CA0017)Wtsi} embryos

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: CA0017
• Germline Transmission: Earliest citation of germline transmission: J:158780
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxf*
• Mutation details: The gene trap vector inserted into the 14th intron. Beta-galactosidase expression was detected in islet and acinar cells. The fusion peptide lacks the Hrd3-like motif, the transmembrane domain, the proline-rich domain, and 4 Sel1lL-like repeats. (J:158780)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CA0017	CZ265947 ; (MGI Seq Detail)	5' RACE	Chr12:91784055-91786886 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Sel1l^{Gt(CA0017)Wtsi} allele

Expression

In Mice Carrying this Mutation:	58 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sel1l Mutation: 34 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)