Ero1b^{Gt(P077G11)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Ero1b^{Gt(P077G11)Wrst}
• Name: endoplasmic reticulum oxidoreductase 1 beta; gene trap P077G11, German Gene Trap Consortium
• MGI ID: MGI:3864866
• Synonyms: ERO1-betaⁱ
• Gene: Ero1b Location: Chr13:12580701-12624422 bp, + strand Genetic Position: Chr13, 5.07 cM
• Alliance: Ero1b^{Gt(P077G11)Wrst} page

Diminished insulin stores and mildly disorganized islets in Ero1b^{Gt(P077G11)Wrst}/Ero1b^{Gt(P077G11)Wrst} mice

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: P077G11
• Germline Transmission: Earliest citation of germline transmission: J:158805
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: FlipROSACeoC-2
• Mutation details: The gene trap vector inserted into intron 14. Immunohistochemistry confirmed the absence of protein in the islets. (J:158805)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  P077G11	CZ293277 ; (MGI Seq Detail)	5' RACE	multiple
  * GRCm39; (strand of gene trap mutagenesis)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ero1b Mutation: 25 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 7 reference(s)