Glmp^{Gt(P084H04)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Glmp^{Gt(P084H04)Wrst}
• Name: glycosylated lysosomal membrane protein; gene trap P084H04, German Gene Trap Consortium
• MGI ID: MGI:3865377
• Synonyms: Ncu-g1^gt
• Gene: Glmp Location: Chr3:88232330-88235938 bp, + strand Genetic Position: Chr3, 38.8 cM, cytoband F1
• Alliance: Glmp^{Gt(P084H04)Wrst} page

Liver fibrosis and splenomegaly in Glmp^{Gt(P084H04)Wrst}/Glmp^{Gt(P084H04)Wrst} mice

Show the 6 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: P084H04
• Germline Transmission: Earliest citation of germline transmission: J:208774
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: FlipROSACeoC-2
• Mutation details: A gene trap vector consisting a neomycin cassette with polyadenylation site was inserted in intron 1. Western blot and PCR analysis showed absence of protein and mRNA expression. (J:208774)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  P084H04	CZ293788 ; (MGI Seq Detail)	5' RACE	Chr3:88232360-88232507 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  5 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Glmp^{Gt(P084H04)Wrst} allele

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Glmp Mutation: 37 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 6 reference(s)