Brwd3^{Gt(RHA090)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Brwd3^{Gt(RHA090)Byg}
• Name: bromodomain and WD repeat domain containing 3; gene trap RHA090, BayGenomics
• MGI ID: MGI:3867498
• Gene: Brwd3 Location: ChrX:107780622-107877978 bp, - strand Genetic Position: ChrX, 47.88 cM
• Alliance: Brwd3^{Gt(RHA090)Byg} page

E9.5 Brwd3^{Gt(RHA090)Byg}/Y chimeras exhibit microcephaly and short tail buds

Show the 6 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: RHA090
• Mouse Generated: Earliest citation of chimera generation: J:160967
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector Vector: pGT0pfs Vector Type: gene trap
• Trapped gene association determined by genome coordinate overlap and strand.
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  RHA090	CZ559248 ; (MGI Seq Detail)	5' RACE	ChrX:107868409-107869101 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  11 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Brwd3 Mutation: 17 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

Additional information on the construction of chimeric mice reported in J:160967 can be found at this link

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)