Mob1b^{Gt(CC0690)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Mob1b^{Gt(CC0690)Wtsi}
• Name: MOB kinase activator 1B; gene trap CC0690, Wellcome Trust Sanger Institute
• MGI ID: MGI:3870385
• Synonyms: Mob1b^tr
• Gene: Mob1b Location: Chr5:88868730-88906314 bp, + strand Genetic Position: Chr5, 43.92 cM, cytoband E2
• Alliance: Mob1b^{Gt(CC0690)Wtsi} page

Skin and hair abnormalities and large paws in tamoxifen treated Mob1a^tm1.1Asuz/Mob1a^tm1.1Asuz Tg(KRT14-cre/ERT)20Efu/0 Mob1b^{Gt(CC0690)Wtsi}/Mob1b^{Gt(CC0690)Wtsi} mice

Show the 6 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: CC0690
• Germline Transmission: Earliest citation of germline transmission: J:193981
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxfT2
• The gene trap vector inserted into intron 1. (J:193981)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CC0690	DU635591 ; (MGI Seq Detail)	5' RACE	Chr5:88868754-88868979 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  9 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Targeting strategy for the generation of the Mob1b^{Gt(CC0690)Wtsi} allele

Tumor Data

List all tumor models in MMHCdb carrying Mob1b^{Gt(CC0690)Wtsi}

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mob1b Mutation: 21 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 8 reference(s)