Bcor^{Gt(DB0053)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Bcor^{Gt(DB0053)Wtsi}
• Name: BCL6 interacting corepressor; gene trap DB0053, Wellcome Trust Sanger Institute
• MGI ID: MGI:3870923
• Gene: Bcor Location: ChrX:11902979-12026594 bp, - strand Genetic Position: ChrX, 6.83 cM, cytoband A1.2
• Alliance: Bcor^{Gt(DB0053)Wtsi} page

Bcor^{Gt(DB0053)Wtsi}/Y chimeras at E8.5 exhibit ventral forebrain fusion and microcephaly

Show the 4 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: DB0053
• Mouse Generated: Earliest citation of chimera generation: J:160967
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector Vector: pGT1lxr
• The gene trap vector inserted between exon 5 and 6. (J:163340)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  DB0053	DU636129 ; (MGI Seq Detail)	5' RACE	ChrX:11921207-11922786 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  23 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Bcor Mutation: 22 strains or lines available

Notes

Additional information on the construction of chimeric mice reported in J:160967 can be found at this link

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)