Lemd2Gt(DD0639)Wtsi
Gene trapped Allele Detail
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Symbol: |
Lemd2Gt(DD0639)Wtsi |
Name: |
LEM domain containing 2; gene trap DD0639, Wellcome Trust Sanger Institute |
MGI ID: |
MGI:3871218 |
Synonyms: |
Lemd2gt |
Gene: |
Lemd2 Location: Chr17:27408574-27423443 bp, - strand Genetic Position: Chr17, 13.82 cM
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Alliance: |
Lemd2Gt(DD0639)Wtsi page
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Mutant Cell Line: |
DD0639 |
Germline Transmission: |
Earliest citation of germline transmission:
J:221495
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Parent Cell Line: |
E14TG2a.4 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Project Collection: |
Sanger Inst. Gene Trap Res.
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Allele Type: |
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Gene trapped (Null/knockout, Reporter) |
Mutation: |
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Insertion of gene trap vector
Vector: pGT1lxrT2
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Mutation details: The gene trap introduced a sequence between exons 3 and 4 of the gene that contains a splice acceptor site (SA), a cDNA encoding the beta-galactosidase reporter linked to neomycin (geo), and a SV40 cleavage/polyadenylation site (pA). While the mutant allele is predicted to generate an ~175-kDa fusion protein, a full length expression product was not detected. Smaller presumptive degredation products were seen on Western blot, albeit at reduced levels.
(J:221495)
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Sequence Tags: |
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Sequence tag details (1 tag)
Tag ID |
GenBank ID |
Method |
Tag Location (trapped strand)* |
Select |
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Genome Context: |
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Genome Browser view of this mutation
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Lemd2 Mutation: |
20 strains or lines available
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Original: |
J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008; |
All: |
2 reference(s) |
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