Osbpl8^{Gt(DD0748)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Osbpl8^{Gt(DD0748)Wtsi}
• Name: oxysterol binding protein-like 8; gene trap DD0748, Wellcome Trust Sanger Institute
• MGI ID: MGI:3871235
• Synonyms: DD00748
• Gene: Osbpl8 Location: Chr10:111000663-111133110 bp, + strand Genetic Position: Chr10, 58.24 cM
• Alliance: Osbpl8^{Gt(DD0748)Wtsi} page

Mutation origin

• Mutant Cell Line: DD0748
• Germline Transmission: Earliest citation of germline transmission: J:199891
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT1lxrT2
• Mutation details: The gene trap vector inserted into intron 5. Western blot analysis confirmed the absence of protein expression in the spleen, brain, kidney, liver and peritoneal macrophages. (J:199891)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  DD0748	DU636442 ; (MGI Seq Detail)	5' RACE	Chr10:111000936-111060554 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  17 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Osbpl8^{Gt(DD0748)Wtsi} allele

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Osbpl8 Mutation: 64 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)