Kdm8^{Gt(AZ0518)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Kdm8^{Gt(AZ0518)Wtsi}
• Name: lysine (K)-specific demethylase 8; gene trap AZ0518, Wellcome Trust Sanger Institute
• MGI ID: MGI:3871554
• Gene: Kdm8 Location: Chr7:125043848-125061441 bp, + strand Genetic Position: Chr7, 68.85 cM, cytoband F3
• Alliance: Kdm8^{Gt(AZ0518)Wtsi} page

Mutation origin

• Mutant Cell Line: AZ0518
• Germline Transmission: Earliest citation of germline transmission: J:182585
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: The gene trap vector inserted after the first 24 bp in exon 3. RT-PCR analysis confirms the absence of expression in homozygous embryos. (J:182585)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AZ0518	DU709077 ; (MGI Seq Detail)	5' RACE	Chr7:125043869-125051510 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	26 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Kdm8 Mutation: 18 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)