Wdr62^{Gt(AF0003)Wtsi}
Gene trapped Allele Detail

Summary

• Symbol: Wdr62^{Gt(AF0003)Wtsi}
• Name: WD repeat domain 62; gene trap AF0003, Wellcome Trust Sanger Institute
• MGI ID: MGI:3876681
• Synonyms: Wdr62^lacZ
• Gene: Wdr62 Location: Chr7:29939563-29979844 bp, - strand Genetic Position: Chr7, 17.34 cM
• Alliance: Wdr62^{Gt(AF0003)Wtsi} page

Mutation origin

• Mutant Cell Line: AF0003
• Germline Transmission: Earliest citation of germline transmission: J:224504
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd
• Project Collection: Sanger Inst. Gene Trap Res.

Mutation description

• Allele Type: Gene trapped (Hypomorph)
• Mutation: Insertion of gene trap vector Vector: pGT0lxr
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. A beta-geo reporter gene-trap vector inserted into the intronic region between exons 14 and 15. Western blot showed a reduction in protein in homozygotes, indicating a hypomorphic allele. (J:224504)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  AF0003	DX574160 ; (MGI Seq Detail)	5' RACE	Chr7:29953610-29954051 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  6 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Wdr62 Mutation: 52 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)