Porcn^{Gt(CSD256)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Porcn^{Gt(CSD256)Byg}
• Name: porcupine O-acyltransferase; gene trap CSD256, BayGenomics
• MGI ID: MGI:3877648
• Gene: Porcn Location: ChrX:8060087-8072764 bp, - strand Genetic Position: ChrX, 3.7 cM
• Alliance: Porcn^{Gt(CSD256)Byg} page

Porcn^{Gt(CSD256)Byg}/Y chimera at E7.5 exhibits abnormal embryonic tissue morphology

Show the 22 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: CSD256
• Mouse Generated: Earliest citation of chimera generation: J:160967
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• The gene trap vector is inserted between exon 1 and 2. (J:163340)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CSD256	DX577273 ; (MGI Seq Detail)	5' RACE	ChrX:8072617-8072729 bp (-)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  15 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Schematic of the Porcn^{Gt(CSD256)Byg} allele

Expression

In Structures Affected by this Mutation:

9 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Porcn Mutation: 18 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

Additional information on the construction of chimeric mice reported in J:160967 can be found at this link

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 7 reference(s)