Aim2^{Gt(CSG445)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Aim2^{Gt(CSG445)Byg}
• Name: absent in melanoma 2; gene trap CSG445, BayGenomics
• MGI ID: MGI:3877800
• Gene: Aim2 Location: Chr1:173178445-173293606 bp, + strand Genetic Position: Chr1, 80.33 cM
• Alliance: Aim2^{Gt(CSG445)Byg} page

Mutation origin

• Mutant Cell Line: CSG445
• Germline Transmission: Earliest citation of germline transmission: J:158969
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: The beta-geo containing gene trap vector inserted into intron 6. The absence of protein expression was confirmed by western blot analysis on thioglycollate-elicited and bone marrow-derived macrophage extracts. (J:158969)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  CSG445	DX812645 ; (MGI Seq Detail)	5' RACE	Chr1:173282897-173283178 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  2 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Aim2 Mutation: 35 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 64 reference(s)