Vrk3^{Gt(YTA189)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Vrk3^{Gt(YTA189)Byg}
• Name: vaccinia related kinase 3; gene trap YTA189, BayGenomics
• MGI ID: MGI:3880442
• Gene: Vrk3 Location: Chr7:44398049-44426939 bp, + strand Genetic Position: Chr7, 28.9 cM
• Alliance: Vrk3^{Gt(YTA189)Byg} page

Mutation origin

• Mutant Cell Line: YTA189
• Germline Transmission: Earliest citation of germline transmission: J:230531
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: The gene trap vector inserted at position 334 in intron 7. Western blot analysis confirmed the absence of full length protein in homozygous mice. (J:230531, J:249352)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  YTA189	EI182854 ; (MGI Seq Detail)	5' RACE	Chr7:44403273-44412478 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  8 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Vrk3 Mutation: 38 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)