Dbr1^{Gt(YTA280)Byg}
Gene trapped Allele Detail

Summary

• Symbol: Dbr1^{Gt(YTA280)Byg}
• Name: debranching RNA lariats 1; gene trap YTA280, BayGenomics
• MGI ID: MGI:3880498
• Gene: Dbr1 Location: Chr9:99457852-99466554 bp, + strand Genetic Position: Chr9, 51.86 cM, cytoband F1
• Alliance: Dbr1^{Gt(YTA280)Byg} page

Mutation origin

• Mutant Cell Line: YTA280
• Germline Transmission: Earliest citation of germline transmission: J:223318
• Parent Cell Line: Other (see notes) (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Hypomorph, Reporter)
• Mutation: Insertion of gene trap vector Vector: pGT0Lxf Vector Type: gene trap
• Mutation details: The beta-geo gene trap inserted into intron 2. RT-PCR confirmed reduced transcript expression in B cells. (J:223318)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  YTA280	EI182910 ; (MGI Seq Detail)	5' RACE	Chr9:99457869-99458750 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dbr1 Mutation: 25 strains or lines available

Notes

All BayGenomics gene trap mutations were generated in either CGR8 or E14TG2a (129P2/OlaHsd) parental ES cell lines, with the majority in subline E14TG2a.4. The specific ES cell line in which each mutation was made is not specified.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)