Grhl2^{Gt(E115B04)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Grhl2^{Gt(E115B04)Wrst}
• Name: grainyhead like transcription factor 2; gene trap E115B04, German Gene Trap Consortium
• MGI ID: MGI:3896011
• Synonyms: Grhl2^LacZ1
• Gene: Grhl2 Location: Chr15:37233280-37363813 bp, + strand Genetic Position: Chr15, 14.84 cM, cytoband C
• Alliance: Grhl2^{Gt(E115B04)Wrst} page

Mutation origin

• Mutant Cell Line: E115B04
• Germline Transmission: Earliest citation of germline transmission: J:167065
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: rFROSAbgeo0s
• Mutation details: Trapped gene association determined by genome coordinate overlap and strand. The gene trap vector was inserted in intron 1. No mRNA could be detected in homozygous embryo extracts. Antibody to the N-terminal region of the protein showed no embryo staining. (J:167065)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  3SE115B04	ER909070 ; (MGI Seq Detail)	3'Splinkerette PCR	Chr15:37262065-37262209 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  46 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Structures Affected by this Mutation:

5 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Grhl2 Mutation: 41 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 4 reference(s)