Tbc1d1^{Gt(E140H06)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Tbc1d1^{Gt(E140H06)Wrst}
• Name: TBC1 domain family, member 1; gene trap E140H06, German Gene Trap Consortium
• MGI ID: MGI:3896754
• Gene: Tbc1d1 Location: Chr5:64313648-64508829 bp, + strand Genetic Position: Chr5, 32.8 cM
• Alliance: Tbc1d1^{Gt(E140H06)Wrst} page

Mutation origin

• Mutant Cell Line: E140H06
• Germline Transmission: Earliest citation of germline transmission: J:203285
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: rFROSAbgeo+2s
• Mutation details: The gene trap vector inserted into intron 2. Western blot analysis confirmed the absence of protein expression in the soleus and extensor digitorum longus muscles. (J:203285)
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  5SE140H06	ER910051 ; (MGI Seq Detail)	5'Splinkerette PCR	Chr5:64409862-64410138 bp (+)
  3SE140H06	ER910050 ; (MGI Seq Detail)	3'Splinkerette PCR	Chr5:64410135-64410207 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  34 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Expression

In Mice Carrying this Mutation:	15 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tbc1d1 Mutation: 80 strains or lines available

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)