Huwe1^{Gt(P125E01)Wrst}
Gene trapped Allele Detail

Summary

• Symbol: Huwe1^{Gt(P125E01)Wrst}
• Name: HECT, UBA and WWE domain containing 1; gene trap P125E01, German Gene Trap Consortium
• MGI ID: MGI:3897892
• Gene: Huwe1 Location: ChrX:150583803-150718413 bp, + strand Genetic Position: ChrX, 68.46 cM
• Alliance: Huwe1^{Gt(P125E01)Wrst} page

Huwe1^{Gt(P125E01)Wrst}/Y chimera at E7.5 fails to gastrulate

Show the 10 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: P125E01
• Mouse Generated: Earliest citation of chimera generation: J:160967
• Parent Cell Line: TBV2 (ES Cell)
• Strain of Origin: 129S2/SvPas

Mutation description

• Allele Type: Gene trapped
• Mutation: Insertion of gene trap vector Vector: ROSAbetageo+2
• Trapped gene association determined by genome coordinate overlap and strand.
• Sequence Tags: Sequence tag details (2 tags)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  3SP125E01	ER912607 ; (MGI Seq Detail)	3'Splinkerette PCR	ChrX:150587600-150587870 bp (+)
  5SP125E01	ER912608 ; (MGI Seq Detail)	5'Splinkerette PCR	ChrX:150587197-150587263 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  75 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Huwe1 Mutation: 63 strains or lines available

Notes

Additional information on the construction of chimeric mice reported in J:160967 can be found at this link

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 3 reference(s)