Syf2^{Gt(PST25562)Mfgc}
Gene trapped Allele Detail

Summary

• Symbol: Syf2^{Gt(PST25562)Mfgc}
• Name: SYF2 homolog, RNA splicing factor (S. cerevisiae); gene trap PST25562, Mammalian Functional Genomics Centre
• MGI ID: MGI:3904866
• Synonyms: mp29^GT
• Gene: Syf2 Location: Chr4:134658291-134664848 bp, + strand Genetic Position: Chr4, 67.15 cM, cytoband D3
• Alliance: Syf2^{Gt(PST25562)Mfgc} page

Aberrant development in Syf2^{Gt(PST25562)Mfgc}/Syf2^{Gt(PST25562)Mfgc} embryos

Show the 1 phenotype image(s) involving this allele.

Mutation origin

• Mutant Cell Line: PST25562
• Germline Transmission: Earliest citation of germline transmission: J:187030
• Parent Cell Line: E14TG2a.4 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Gene trapped (Null/knockout, Reporter)
• Mutation: Insertion of gene trap vector Vector: U3NeoSVFS
• Mutation details: The gene trap vector inserted into intron 2. Western blot analysis confirmed the absence of protein expression in embryos at E7.5. (J:187030)
• Sequence Tags: Sequence tag details (1 tag)

  Tag ID	GenBank ID	Method	Tag Location (trapped strand)*	Select
  PST25562-NR	ET029830 ; (MGI Seq Detail)	plasmid rescue	Chr4:134658934-134659131 bp (+)
  * GRCm39; (strand of gene trap mutagenesis)

• Genome Context: Genome Browser view of this mutation;

  3 gene trap insertions have trapped this gene; View all gene trap sequence tags in this region

Generation of the Syf2^{Gt(PST25562)Mfgc} allele

Expression

In Mice Carrying this Mutation:

35 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Syf2 Mutation: 13 strains or lines available

Notes

This gene trap is no longer available through the Toronto Centre for Phenogenomics.

References

• Original: J:141210 Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI), Mouse Gene Trap Data Load from dbGSS. Database Download. 2008
• All: 2 reference(s)